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目前治疗真菌性角膜炎缺少广谱高效和低毒的抗真菌药物,特比萘芬是90年代合成的一类结构新颖的烯丙胺类(allylamines)药物,治疗浅层角膜真菌感染性疾病取得显著疗效,但对眼部真菌的抗菌作用报道较少。作者曾采用微量液基稀释法比较了七种抗真菌药物的最小抑菌浓度(MIC),结果显
At present, the treatment of fungal keratitis lacks broad-spectrum high-efficiency and low-toxicity antifungal drugs. Terbinafine is a novel class of allylamines synthesized in the 1990s and has achieved remarkable results in the treatment of superficial corneal fungal infections Curative effect, but the antibacterial effect of eye fungi reported less. The authors used micro-liquid-based dilution method compared the minimum inhibitory concentration (MIC) of seven antifungal agents, the results were significant