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目的探讨胃癌复发的类型、复发时间和危险因素,为预测和预防胃癌根治术后复发提供依据。方法回顾性分析1994年8月至1999年8月我科收治的48例胃癌复发病例的复发类型、复发时间和原发胃癌的临床病理特征,并任取我科同期收治的48例无复发胃癌病例作对照。用单因素和多因素分析研究胃癌复发和短期内复发的相关因素。结果单因素分析结果显示,复发组病例术前存在盆腔转移结节、浸润深度达浆膜或浆膜以外以及Borrmann分型Ⅲ型和Ⅳ型的比例明显增多,差异具有统计学意义(P<0.05)。多因素Logistic回归分析表明,浸润深度和Borrmann分型是胃癌复发的高危因素。COX回归分析显示,初发胃癌的浸润深度和腹水是影响胃癌根治手术后早期复发的主要因素。结论Borrmann分型是胃癌复发的高危因素,腹水是影响胃癌根治手术后早期复发的主要因素,而浸润深度既是胃癌复发的高危因素也是胃癌早期复发的主要因素。
Objective To investigate the type, recurrence time and risk factors of gastric cancer recurrence and provide basis for predicting and preventing the recurrence of gastric cancer after radical surgery. Methods Retrospective analysis of recurrence type, recurrence time and clinicopathological features of 48 cases of recurrent gastric cancer admitted to our department from August 1994 to August 1999 were retrospectively analyzed. 48 patients with recurrent gastric cancer Case as a control. Using univariate and multivariate analysis to study the related factors of gastric cancer recurrence and short-term recurrence. Results The results of univariate analysis showed that there were pelvic metastasis nodules in the recurrence group, the infiltration depth beyond the serosal or serosal membrane and Borrmann type Ⅲ and Ⅳ significantly increased, the difference was statistically significant (P <0.05 ). Multivariate Logistic regression analysis showed that the depth of invasion and Borrmann’s classification were the risk factors of gastric cancer recurrence. COX regression analysis showed that the infiltration depth and ascites of primary gastric cancer were the main factors affecting the early recurrence of gastric cancer after radical surgery. Conclusion Borrmann classification is a risk factor for gastric cancer recurrence. Ascitic fluid is a major factor affecting the early recurrence of gastric cancer after radical operation. Invasive depth is not only the risk factor of gastric cancer recurrence but also the main factor of early gastric cancer recurrence.