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各种恶性血液病可直接侵犯中枢神经系统(CNS).为确定其发病率、预后意义和尝试建立合理治疗措施,作者复习了1979-1987年间经治的540例.包括何杰金病(HD)、非何杰金淋巴瘤(NHL)、按FAB分类的急淋(ALL)和急非淋白血病(ANLL).受累的解剖学三种类型:弥漫性软脑膜病、硬膜外赘生物和颅内肿块,分别经姬姆萨染色脑脊液离心分离细胞、脊髓X线造影和颅CT确诊.前者联用放化疗,后两者经局部放疗处理.结果表明106例ANLL可分析的71例仅1例在全身缓解期出现弥漫软脑膜病,7个月后死于全
A variety of hematologic malignancies can directly invade the central nervous system (CNS) .In order to determine its incidence, prognostic significance and attempt to establish a reasonable treatment, the authors reviewed 540 cases treated during 1979-1987, including Hodgkin’s disease ), Non-Hodgkin lymphoma (NHL), FAB-classified acute lymphoblastic leukemia (ALL), and acute non-lymphoid leukemia (ANLL). There are three types of anatomic involvement: diffuse leptomeniosis, epidural neoplasms Intracranial masses were separated by Giemsa staining of cerebrospinal fluid by centrifugation, spinal cord radiography and cranial CT diagnosis of the former combined with radiotherapy and chemotherapy, the latter two by local radiotherapy treatment results show that 106 cases of ANLL can be analyzed in 71 cases only 1 Cases of diffuse pia mater meningitis in the general remission period, died in seven months after the whole