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目的:对新型冠状病毒肺炎（COVID-19）康复者的ABO血型分布做出统计，并进一步分析具有不同恢复期血浆抗严重急性呼吸系统综合征冠状病毒2（severe acute respiratory syndrome coronavirus 2, SARS-CoV-2）抗体效价的康复者的ABO血型分布。方法:抽取150份年龄18~60岁的COVID-19康复者血浆作为实验组，患者达到出院标准后14 d采集血浆。另抽取武汉市180例健康人的血型作为健康对照组。分析年龄、性别与康复者ABO血型分布的关联性。同时分析康复者血浆中抗体的效价及其于ABO血型的关联。结果:和健康对照组相比，COVID-19康复者中B型血患者数量较多（36% n vs 25.0%, χn 2=4.714, n P<0.05）。性别与COVID-19康复者ABO血型分布无关联性，而年龄与COVID-19康复者ABO血型分布有关联，在40岁以下组中，B型血COVID-19康复者数量较健康对照组增多（38.5%n vs 25.0%, χn 2=5.264, n P<0.05）。5.3%康复者血浆中抗SARS-CoV-2抗体效价≤1∶80。和健康对照组相比，在高血浆抗SARS-CoV-2抗体效价组中，B型血COVID-19康复者数量较多（35.2% n vs 25.0%, χn 2=3.979, n P<0.05）。n 结论:COVID-19康复者中，40岁以下、B型血患者数量较多；部分血浆抗SARS-CoV-2抗体效价较低的康复者不具备捐赠血浆的条件；而B型血康复者可能更适宜作为COVID-19恢复期血浆捐献对象。“,”Objective:To perform a statistical analysis of the ABO blood group distribution of COVID-19 convalescents, and further analyze the ABO blood group distribution in COVID-19 convalescents with different plasma antibody titer against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).Methods:Convalescent plasma was collected from 150 patients aged 18-60 years old who had recovered from COVID-19. Convalescent plasma was collected 14 days later after patients discharged from hospital, and another 180 normal people in Wuhan city were served as healthy control group. Then we analyzed the relationship between age, gender and the ABO blood group distribution. We also tried to clarify the relationship between plasma antibody liter against SARS-CoV-2 and the ABO blood group distribution.Results:Compared with the healthy control group, the proportion of blood group B in COVID-19 convalescents was higher (36% n vs 25.0%, χ n 2=4.714, n P<0.05). The ABO blood group distribution did not differ from male and female COVID-19 convalescents, while age affected the ABO blood group distribution of COVID-19 convalescents. Among the age group under 40 years old, the proportion of blood group B in COVID-19 convalescents was higher than that in the healthy control group (38.5% n vs 25.0%, χ n 2=5.264, n P<0.05). The antibody titer against SARS-CoV-2 in 5.3% of the convalescent plasma was under 1:80. In the high antibody liter against SARS-CoV-2 group, the proportion of blood group B in COVID-19 convalescents was higher than that in the healthy control group (35.2% n vs 25.0%, χ n 2=3.979, n P<0.05).n Conclusions:COVID-19 convalescents with blood group B and age group under 40 years old have a higher proportions than that in the normal people. Part of the convalescents with lowantibody liter against SARS-CoV-2 didn’t meet the conditions for plasma donation. Convalescents with blood group B may be more suitable as plasma donators for the therapy of COVID-19.