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血小板α颗粒膜蛋白(GMP-140),血小板表面相关抗体(PAIg G A M)的表达,提示了血小板功能的改变。正常血小板并不存在GMP-140,其PAIg 亦不应表达。乙肝患者由于长期受HBV侵害,骨髓受到不同程度损伤,或者血小板受到病毒或毒素刺激后发生活化,释放胞内颗粒内容物,使血小板
The expression of platelet-derived granule membrane protein (GMP-140) and platelet surface associated antibody (PAIg G A M) suggests a change in platelet function. Normal platelets do not exist GMP-140, the PAIg should not be expressed. Hepatitis B patients due to long-term by HBV damage, bone marrow damage to varying degrees, or platelets by the virus or toxin activation occurs after activation, the release of intracellular particle content, so that platelets