抗生素诱发腹泻是抗生素治疗过程中出现的一种并发症。近年来抗生素的使用对正常菌群的影响，特别是对肠道菌群的影响已引起了医务工作者的普遍重视。正常菌群在机体的免疫、营养、消化、吸收、防御疾病以及保持宿主与外环境的平衡性等方面起重要作用〔１〕。由于内在或外在的因素生态平衡被破坏，就会引起菌群失调，而广谱抗生素的应用最易改变肠道菌群的正常生态平衡，导致发病。 Antibiotic-induced diarrhea is a complication of antibiotic therapy. In recent years, the use of antibiotics on the normal flora, especially on the intestinal flora has drawn the medical practitioner’s universal attention. Normal flora in the body’s immune, nutrition, digestion, absorption, disease prevention and maintain the balance between the host and the environment play an important role 〔1〕. Due to the internal or external factors of ecological balance is destroyed, it will cause flora, and broad-spectrum antibiotics most likely to change the normal ecological balance of intestinal flora, leading to the disease.