论文部分内容阅读
荧光原位杂交 (ＦＩＳＨ)是一种高度灵敏和特异性以及分辨率强的染色体和基因的分析技术 ,使用非放射性探针与靶细胞的ＤＮＡ杂交 ,通过荧光显色 ,可以直接观察分析细胞核中或染色体上的ＤＮＡ序列变化或位置改变。由于大于 50ｂＰ的ＤＮＡ序列缺失和易位均可用ＦＩＳＨ技术识
Fluorescence in situ hybridization (FISH) is a highly sensitive and specific, high resolution chromosomal and genetic analysis technique that uses non-radioactive probes to hybridize to DNA from target cells and allows direct visualization of the nucleus by fluorescence Or DNA sequence changes or changes in position on the chromosome. As more than 50bP DNA sequence loss and translocation are available FISH technology knowledge