本文回顾分析我院２８１例次尸肾移植，术后早期发生急性肾小管坏死（ＡＴＮ）５１例（占１８％）。通过采用血液透析、利尿药、扩肾血管药以及免疫抑制剂ＡＬＧ等治疗，３１例（占６１％）恢复肾功能。预防方法：提高取肾质量、缩短热、温缺血时间，避免术中、术后血压过低以及保养液中添加钙离子拮抗剂等 This article retrospectively analyzed 281 cases of cadaveric renal transplantation in our hospital, and 51 cases (18%) of acute tubular necrosis (ATN) occurred early after operation. Through the use of hemodialysis, diuretics, vasodilators and immunosuppressive agents such as ALG treatment, 31 cases (61%) to restore renal function. Prevention: improve renal quality, shorten the warm, warm ischemic time, to avoid intraoperative and postoperative blood pressure is too low, as well as the maintenance fluid to add calcium antagonists