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目的观察归脾汤联合茶碱缓释片治疗窦性心动过缓的临床疗效。方法将2011年1月-2015年10月医院综合科收治的46例窦性心动过缓患者随机分为对照组和治疗组各23例。对照组在常规治疗基础上给予茶碱缓释片辅治[1]。治疗组在对照组用药基础上配合口服归脾汤加减进行治疗。观察2组治疗前后的临床疗效及不良反应。结果治疗后2组患者的临床症状、体征及心电变化有明显改善。治疗组总有效率为95.7%明显高于对照组的78.3%,差异有统计学意义(P<0.05)。窦性心动过缓总有效率91.3%明显高于对照组的69.6%,差异有统计学意义(P<0.05)。且所有患者治疗期间均未发生不良反应。结论归脾汤联合茶碱缓释片治疗窦性心动过缓临床疗效好,治疗过程中未发生不良反应,值得临床推广应用。
Objective To observe the clinical effects of Guipi Decoction combined with theophylline sustained release tablets in treatment of sinus bradycardia. Methods From January 2011 to October 2015, 46 cases of sinus bradycardia admitted to the hospital general department were randomly divided into control group and treatment group of 23 cases. The control group was given theophylline sustained-release tablets on the basis of routine treatment [1]. The treatment group in the control group based on the medication with oral Guipi Decoction for treatment. The clinical efficacy and adverse reactions of two groups before and after treatment were observed. Results After treatment, the clinical symptoms, signs and ECG changes in 2 groups were significantly improved. The total effective rate was 95.7% in the treatment group was significantly higher than 78.3% in the control group, the difference was statistically significant (P <0.05). The total effective rate of sinus bradycardia 91.3% was significantly higher than 69.6% of the control group, the difference was statistically significant (P <0.05). And no adverse reactions occurred in all patients during treatment. Conclusion Guipi Decoction combined with theophylline sustained-release tablets in the treatment of sinus bradycardia clinical efficacy, no adverse reactions in the course of treatment, it is worth promoting the clinical application.