药物应用的概念模式一种实用的药物应用概念模式表明,在选定一种药物后原则上其药理作用可能对某一病人有益,它的效力只有当给药途径、剂量和给药时间都选择适当时才能达到最大。所有这些特点称为“给药方案”。给药方案将确定最终疗效,因为药物的剂量(通过任何途径)将产生其组织浓度,包括药物要起作用的组织。药物在作用部位可能与受体互相作用 Conceptual model of drug use A useful conceptual model of drug application suggests that the pharmacological effect in principle may be beneficial to a patient after the selection of a drug, and its efficacy is only when the route of administration, dosage and timing of administration are chosen Appropriate to achieve maximum. All of these features are called “dosing regimens.” The dosing regimen will determine the ultimate efficacy, as the dosage of the drug (by any route) will produce its tissue concentration, including the tissue where the drug is to act. The drug may interact with the receptor at the site of action