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为了增加生物医用钛及其合金的生物活性和其他特殊功能,对钛合金表面进行改性和功能化。采用阳极氧化法在钛合金表面制备出TiO2纳米管阵列,再用真空浸渍法制备载银TiO2纳米管阵列;研究了载银TiO2纳米管阵列的抗菌作用。结果表明:阳极氧化法使钛合金表面形成高度整齐的TiO2纳米管阵列,其管径为150~200nm,管长为400~500nm,管壁厚为20nm,且纳米银颗粒沉积在纳米管的管口及管壁上,其粒径约为10~20nm。在磷酸盐缓冲液中,银离子释放时间至少能够持续13d。该载银TiO2纳米管阵列对金黄葡萄球菌和大肠杆菌具有一定的抑制作用。
In order to increase the biological activity of biomedical titanium and its alloys and other special functions, the titanium alloy surface is modified and functionalized. The TiO2 nanotube array was prepared on the surface of titanium alloy by anodic oxidation and the silver-loaded TiO2 nanotube array was prepared by vacuum impregnation. The antibacterial activity of the silver-loaded TiO2 nanotube array was studied. The results show that the anodic oxidation method forms a highly ordered TiO2 nanotube array on the surface of titanium alloy with a diameter of 150-200 nm, a tube length of 400-500 nm and a tube wall thickness of 20 nm. The nano-silver particles are deposited on the tube of the nanotube Mouth and tube wall, the particle size of about 10 ~ 20nm. In phosphate buffer, silver ion release time can last at least 13d. The silver-loaded TiO2 nanotube array has a certain inhibitory effect on Staphylococcus aureus and Escherichia coli.