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目的分析常熟地区2005—2008年狂犬疫苗免疫效果和不同性别、年龄、年份以及季节等因素对免疫效果的影响。方法采用间接ELISA方法对5 471例全程足量注射狂犬疫苗者进行抗体检测分析。结果本调查人群总的抗体阳性率为94.3%,抗体阳性率女性高于男性,0～9岁高于其它年龄组。随着年份的增加,抗体阳性率呈增加趋势,同时,在季节分布上,第3季度抗体的阳性率低于其它3个季度。结论受动物致伤后要及时全程注射狂犬疫苗,免疫后检测血清抗体水平十分重要,对暂未产生抗体者要及时加强免疫,确保免疫效果。
Objective To analyze the immune effects of rabies vaccine in Changshu area from 2005 to 2008 and the effects of different factors such as sex, age, year and season on the immune effect. Methods The indirect ELISA method was used to detect the antibody in 5 471 rabies vaccines. Results The total positive rate of antibody in this survey population was 94.3%. The positive rate of antibody was higher in women than in men and was higher in 0-9 years than in other age groups. The antibody positive rate showed an increasing trend with the increase of the year. Meanwhile, in the season distribution, the positive rate of the antibody in the third quarter was lower than the other three quarters. Conclusion It is very important to detect rabies vaccine in rabbits after the animal is injured. It is very important to detect the level of serum antibody after immunization. In the case of antibody that has not yet been produced, it is necessary to strengthen immunity in time to ensure the immune effect.