阿曲可林(Atracurium)是一种中效非去极化神经肌肉阻滞剂,作用点在神经肌肉接头。作用持续时间为15～30分钟,对肝肾功能无明显影响。现就其药代动力学方面作一简述。一、降解途经阿曲可林进入体内,在生理体温和正常 pH 情况下,通过自身结构破坏的“霍夫曼作用”(Hofma Atracurium is a moderate-acting nondepolarizing neuromuscular blocker that acts at the neuromuscular junction. Duration of action for 15 to 30 minutes, no significant effect on liver and kidney function. Now on its pharmacokinetics to make a brief. First, the degradation of Alcalase into the body through the body, at physiological body temperature and normal pH, through its own structural destruction of the “Huffman effect” (Hofma