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目的:探讨ANCA相关性血管炎(AAV)采取激素+环磷酰胺+腹膜透析治疗的疗效情况。方法:选取60例于2009年3月至2011年3月期间我院接收的AAV患者,将入选患者平分为对照组与实验组,两组分别给予激素和激素+环磷酰胺+腹膜透析治疗,观察两组临床治疗疗效。结果:治疗1个月后,实验组在24h尿蛋白定量、BVAS、CRP、Scr的改善较对照组明显(P<0.05);且治疗1个月后,实验组ANCA转阴率较对照组明显要高。结论:ANCA相关性血管炎患者采取腹膜透析治疗,联合环磷酰胺、甲泼尼龙免疫对缓解肾脏损害、控制血管炎病情活动,值得推广。
Objective: To investigate the curative effect of ANCA-associated vasculitis (AAV) treated with hormone + cyclophosphamide + peritoneal dialysis. Methods: Sixty AAV patients received in our hospital from March 2009 to March 2011 were selected and divided into control group and experimental group. The two groups were treated with hormone and hormone + cyclophosphamide + peritoneal dialysis respectively, Observation of two groups of clinical curative effect. Results: After 1 month of treatment, the urinary protein excretion, BVAS, CRP and Scr in experimental group were significantly improved than those in control group (P <0.05). After 1 month of treatment, the negative rate of ANCA in experimental group was significantly lower than that in control group To be high. Conclusion: ANCA-associated vasculitis patients take peritoneal dialysis treatment, combined with cyclophosphamide, methylprednisolone immunization to alleviate kidney damage, vasculitis disease activity, worth promoting.