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手术病人术后2天和7天外周血单个核细胞(PBMC)的T淋巴细胞转化及白介素2(IL2)的生成均明显降低。50~250μg/ml的黄芪多糖(APS)、0.1~100μg/ml的人参茎叶皂甙(GSL)在体外对术后7天PBMC的T淋巴细胞转化及IL2的生成均具有不同程度的升高作用,表明APS、GSL对手术病人PBMC具有直接的刺激活性。
Peripheral blood mononuclear cell (PBMC) T lymphocyte transformation and interleukin 2 (IL-2) production were significantly reduced at 2 days and 7 days after surgery. 50~250μg/ml astragalus polysaccharides (APS) and 0.1~100μg/ml Ginseng stem and leaf saponins (GSL) have different degrees of in vitro T lymphocyte transformation and IL2 production of PBMCs 7 days after surgery. The elevated effect indicates that APS and GSL have direct stimulatory activity on PBMC in surgical patients.