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原发性三叉神经痛的病因与发病机制仍不清楚。随着现代微创神经外科的开展以及医学影像学的发展,通过术前磁共振检查和术中观察可见到血管对神经的压迫和微血管减压手术治疗有效,使得神经血管压迫导致原发性三叉神经痛这一观点逐渐被很多研究者接受。但也有一些研究者不认同该理论,提出无症状的神经血管关系密切为常见现象;临床上仍有一些不能用神经血管压迫理论来解释的表现;微血管减压术治疗的有效性与手术对三叉神经的创伤有关。也有研究表明中枢机制在三叉神经痛上起主要作用。针对神经血管压迫学说的争论进行综述。
The etiology and pathogenesis of primary trigeminal neuralgia remains unclear. With the development of modern minimally invasive neurosurgery and the development of medical imaging, preoperative MRI and intraoperative observation can be seen vascular compression and microvascular decompression surgery is effective, making the nerve blood vessels lead to the primary trigeminal The idea of neuralgia is gradually accepted by many researchers. However, some researchers do not agree with the theory and propose that asymptomatic neurovascular relations are closely related to each other. There are still some clinical manifestations that can not be explained by the theory of neurovascular compression. The effectiveness of microvascular decompression in the treatment of the trigeminal Nerve trauma related. Research has also shown that the central mechanism plays a major role in trigeminal neuralgia. A review of the debate about neurovascular compression theory.