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目的:观察盐酸伐昔洛韦片联合白芍总苷胶囊治疗带状疱疹的临床疗效。方法:将56例带状疱疹随机分为对照组与观察组,每组28例。对照组予盐酸伐昔洛韦片治疗;观察组予盐酸伐昔洛韦片联合白芍总苷胶囊治疗。共治疗2周。结果:总有效率观察组96.4%,对照组67.9%,2组比较,差异有统计学意义(P<0.01)。观察组止疱时间、止痛时间、结痂时间低于对照组,2组比较,差异有统计学意义(P<0.01)。2组不良反应发生情况比较,差异无统计学意义(P>0.05)。结论:盐酸伐昔洛韦片联合白芍总苷胶囊治疗带状疱疹的临床效果显著,可能与白芍总苷胶囊有免疫双向调节、抗炎止痛有关。
Objective: To observe the clinical efficacy of valacitovir hydrochloride tablets combined with total glucosides of paeony in treating herpes zoster. Methods: 56 cases of herpes zoster were randomly divided into control group and observation group, 28 cases in each group. The control group was treated with valacyclovir hydrochloride tablets. The observation group was treated with valacyclovir hydrochloride tablets and total glucosides of paeony. A total of 2 weeks treatment. Results: The total effective rate was 96.4% in the observation group and 67.9% in the control group. There was significant difference between the two groups (P <0.01). The observation group blister time, analgesic time, scab time is lower than the control group, the two groups, the difference was statistically significant (P <0.01). There was no significant difference in adverse reactions between the two groups (P> 0.05). Conclusion: Valacyclovir hydrochloride tablets combined with total glucosides of paeony are effective in treating herpes zoster, which may be related to immune bidirectional regulation of anti-inflammatory drugs and anti-inflammatory and analgesic effects.