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目的：观察脉络宁注射液和复方丹参注射液治疗急性缺血性中风的临床疗效；并探讨脉络宁注射液的临床疗效与给药时间、药物剂量及中医证型的关系。方法：将急性缺血性中风患者５０２例随机分为脉络宁注射液治疗组３７７例和复方丹参注射液对照组１２５例，连续治疗１４日～２８日。结果：脉络宁注射液的基本显效率（７０．０３％）及总有效率（９５．７６％）均明显优于对照组（２６．４０％和８１．６０％），Ｐ均＜０．０１。时效关系：脉络宁注射液的起效时间在７日，持续作用到１４日；量效关系：脉络宁注射液每日４０ｍｌ为治疗的最佳剂量；证效关系：脉络宁注射液可广泛应用于急性缺血性中风的各个中医证型。结论：脉络宁注射液更适合于急性缺血性中风的治疗
Objective: To observe the curative effect of Mailuoning injection and compound Salvia miltiorrhiza injection on acute ischemic stroke, and to explore the clinical curative effect of Mailuoning injection on the administration time, drug dosage and TCM syndrome type. Methods: A total of 502 acute ischemic stroke patients were randomly divided into Mailuoning injection group (377 cases) and compound Salvia miltiorrhiza injection group (125 cases) for continuous treatment from 14th to 28th. Results: The basic effective rate (70.03%) and total effective rate (95.76%) of Mailuoning injection group were significantly better than that of the control group (26.40% and 81.60%), P <0.01 . Aging relationship: Mailuoning injection of the onset time in the 7th, lasting effect on the 14th; The dose-effect relationship: Mailuoning injection daily 40ml for the treatment of the best dose; Effect relationship: Mailuoning injection can be widely used Acute ischemic stroke in various TCM syndromes. Conclusion: Mailuoning injection is more suitable for the treatment of acute ischemic stroke