目的研究提取番泻叶中二蒽酮的工艺条件。方法采用正交实验法,以番泻苷A含量为指标,对影响提取的各种因素进行研究。结果番泻叶中二蒽酮的最佳提取工艺为:番泻叶中粉以3倍量体积分数50%乙醇浸泡12h,用6倍量体积分数50%乙醇以10mL.min-1的流速渗漉提取。番泻苷A的提取率为86.5%。结论该方法具有简便易行,成本低,效果好的特点。 Objective To study the extraction conditions of diterpenoids from Senna leaves. Methods Orthogonal experiment method was used to determine the sinosome A content as an index and various factors affecting the extraction were studied. Results The optimum extraction process of diterpenes in Senna leaves was as follows: Senna leaf powder was soaked in 30% volume fraction 50% ethanol for 12 hours, and was permeated with 6 times volume fraction 50% ethanol at a flow rate of 10 mL.min-1.漉 extract. The extraction rate of sennoside A was 86.5%. Conclusion This method has the characteristics of simplicity, low cost and good effect.