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目的 :探讨糖尿病合并急性脑梗塞患者血清果糖胺与神经功能缺损程度的关系 ;方法 :根据空腹血糖、果糖胺测定结果 ,结合既往糖尿病史 ,以及头颅CT检查 ,筛选出 76例确诊为糖尿病且合并有急性脑梗塞的患者 ,分为果糖胺正常组和果糖胺升高组 ,采取定量化方法 ,分别在入院时和第 3周对患者的神经功能缺损程度进行评分 ,以判断病情和预后 ;结果 :果糖胺升高组入院分数水平较果糖胺正常组高 (P<0 .0 1 ) ,提示临床病损较重 ;而转归分数水平较后者低 (P <0 .0 1 ) ,提示病情恢复较差 ;结论 :测定糖尿病合并急性脑梗塞患者的血清果糖胺水平对监测病情、指导治疗和估计预后有较大意义
Objective: To investigate the relationship between serum fructosamine and neurological impairment in patients with diabetes mellitus complicated with acute cerebral infarction.Methods: According to the results of fasting blood glucose and fructosamine, combined with the history of diabetes mellitus and head CT examination, 76 patients with diabetes mellitus Patients with acute cerebral infarction were divided into the normal fructosamine group and the elevated fructosamine group. Quantitative methods were used to score the patients’ neurological deficits on admission and in the third week to determine the condition and prognosis. Results : The fructosamine elevated group admission scores higher than the normal fructosamine group (P <0.01), suggesting that the clinical lesions were heavier; and the prognosis score was lower than the latter (P <0.01), suggesting Poor recovery of the disease; Conclusion: The determination of serum fructosamine in patients with diabetes mellitus and acute cerebral infarction has great significance in monitoring the disease, guiding the treatment and estimating the prognosis