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儿童侵袭性肺真菌感染(IPFI)是指真菌侵入儿童气管、支气管及肺组织,引起炎症性反应及组织损伤的感染性疾病,其发病率占深部真菌感染的首位[1]。本病主要与不正规使用广谱抗生素、免疫抑制药等因素有关,近年来发病率有逐年增高趋势。因小儿患者临床表现缺乏特异性,难以取得确切的诊断依据,导致漏诊率、误诊率、病死率显著高于成年患者,因此提高临床早期诊断率并给予正确治疗尤为重要[2]。近年来,
Invasive pulmonary fungal infection in children (IPFI) refers to fungal invasion of children’s trachea, bronchus and lung tissue, causing inflammatory reactions and tissue damage in infectious diseases, the incidence of deep fungal infection in the first place [1]. The disease mainly with irregular use of broad-spectrum antibiotics, immunosuppressive drugs and other factors, the incidence in recent years have increased year by year trend. Due to the lack of specificity of pediatric patients with clinical manifestations, it is difficult to obtain the exact diagnosis, resulting in missed diagnosis rate, misdiagnosis rate and mortality rate were significantly higher than adult patients, so to improve the clinical early diagnosis rate and give the correct treatment is particularly important [2]. In recent years,