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Flomoxef(FMOX,6315-S)是继Latamoxef(LMOX)之后,由盐野义制药研究所开发的头孢噻吩系注射用广谱抗生素。化学结构如附图,其头孢噻吩骨架的7位侧链上有二氟甲基硫代乙酰基,3位为1-(2-羟乙基)-1H-四唑-5-硫(HTT)基。 FMOX属β-内酰胺类抗生素,它不仅显示了对革兰氏阴性菌(绿脓杆菌除外)以
Flomoxef (FMOX, 6315-S) is a broad-spectrum antibiotic cefotaxime for injection developed by Yoshinoyama Laboratory after Latamoxef (LMOX). The chemical structure is shown in the accompanying drawings. The difluoromethylthioacetyl group on the 7-side chain of the cefalotin skeleton and the 1- (2-hydroxyethyl) -1H-tetrazole-5-thio (HTT) base. FMOX is a beta-lactam antibiotic that not only shows resistance to Gram-negative bacteria (other than Pseudomonas aeruginosa)