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目的探讨注射用尤瑞克林治疗心源性脑栓塞患者的治疗效果。方法选取2016年1月—6月营口市中心医院收治的心源性脑栓塞患者74例为研究对象,随机分为观察组与对照组,每组37例。两组患者均给予常规治疗,观察组患者在常规治疗基础上联合注射用尤瑞克林治疗,比较两组患者治疗前后神经功能缺损变化情况;所有患者均随访3个月,观察其日常生活能力改善情况,并比较两组患者的治疗有效性及安全性。结果观察组与对照组患者治疗前NIHSS评分及ADL评分差异均无统计学意义(均P>0.05);观察组患者治疗1周后NIHSS评分低于对照组,随访3个月ADL评分高于对照组,差异均有统计学意义(均P<0.05);观察组患者治疗的总有效率为94.6%,高于对照组的75.7%,差异有统计学意义(P<0.05);观察组的梗死性出血率为10.8%,略低于对照组的13.5%,但差异无统计学意义(P>0.05)。结论注射用尤瑞克林治疗心源性脑栓塞效果显著,且药物安全性高。
Objective To investigate the therapeutic effect of uracil for injection on patients with cardiogenic cerebral embolism. Methods Seventy-four patients with cardiogenic cerebral embolism admitted from January 2016 to June 2016 in Yingkou Central Hospital were randomly divided into observation group and control group, with 37 cases in each group. The two groups of patients were given conventional treatment. The patients in the observation group were treated with ureclin by combination therapy on the basis of routine treatment. The changes of neurological deficits in both groups before and after treatment were compared. All patients were followed up for 3 months to observe their daily living ability Improve the situation, and compare the two groups of patients the effectiveness and safety of treatment. Results There was no significant difference in NIHSS score and ADL score between observation group and control group before treatment (all P> 0.05). The NIHSS score of observation group was lower than that of control group after 1 week of treatment. ADL score of observation group was higher than that of control group (P <0.05). The total effective rate of the treatment group was 94.6%, which was higher than that of the control group (75.7%), the difference was statistically significant (P <0.05) Sexual bleeding rate was 10.8%, slightly lower than the control group of 13.5%, but the difference was not statistically significant (P> 0.05). Conclusion Erilecin injection for the treatment of cardioembolic cerebral infarction effect is significant, and drug safety.