作者测定了20例长期透析的尿毒症息者血浆和血小板vWF浓度,并分析其多聚体构型。20例(男13例,女7例,年龄25～72岁)患者中9例为肾小球肾炎,5例囊性肾病,2例狼疮性肾病,糖尿病肾病和反流性肾病各1例,原因不明的肾功能衰竭2例。全部患者近2个多月未接受过血液制品,近2周未服用抗血小板药。对照组为40名正常人。测定项目为vWF多聚体构型、出血时间(BT)、vWF抗原 The authors measured plasma and platelet vWF concentrations in 20 long-term dialysis uremic patients and analyzed their multimeric configuration. Nine of 20 patients (13 males and 7 females, aged 25-72 years) had glomerulonephritis, 5 cases of cystic nephropathy, 2 cases of lupus nephropathy, 1 case of diabetic nephropathy and 1 case of reflux nephropathy, Two cases of unexplained renal failure. All patients nearly 2 months did not receive blood products, nearly 2 weeks did not take antiplatelet drugs. The control group was 40 normal people. Measurement items for vWF multimeric configuration, bleeding time (BT), vWF antigen