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1968年人们认识了淋巴细胞的两个主要亚类—T淋巴细胞和B淋巴细胞。以后的研究进一步证明,可以根据表面标志的不同,将T细胞分成两个功能不同的亚群,即带Lyt-1和L3T4表面抗原的TH细胞和带Lyt-2表面抗原的Ts/TC细胞。然而T_H和Ts细胞仍然是不均一的细胞群,Ts细胞可以再分为Ts1、Ts2和Ts3亚群,而T_H细胞由于辅助B细胞的方式不同,以及对尼龙毛柱的粘附性不同等,也可以再分为T_(H1)和T_(H2)两个亚类。这方面的进展情况我们以前曾作过介绍。近些年来,由于T细胞克隆技术的发展,各种新淋巴因子(如IL-2,
In 1968 people recognized two main subclasses of lymphocytes, T lymphocytes and B lymphocytes. Subsequent studies further demonstrate that T cells can be divided into two functionally distinct subsets, TH cells with Lyt-1 and L3T4 surface antigens and Ts / TC cells with Lyt-2 surface antigen, depending on the surface marker. However, T_H and Ts cells are still heterogeneous cell populations, Ts cells can be subdivided into Ts1, Ts2 and Ts3 subsets, T_H cells due to different ways of assisting B cells and different adhesion to the nylon hair column, Can also be divided into T_ (H1) and T_ (H2) two subclasses. We have introduced this progress in the past. In recent years, due to the development of T cell cloning technology, various new lymphokines (such as IL-2,