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目的 调查中国类风湿关节炎（ Ｒ Ａ） 病人的临床抑郁情况。方法 ９５ 例未经治疗的初诊活动性 Ｒ Ａ 病人填写抑郁自评量表（ｓｅｌｆｒａｒｉｎｇ ｄｅｐｒｅｓｓｉｏｎ ｓｃａｌｅ ， Ｓ Ｄ Ｓ） 。结果 ５３ ％ Ｒ Ａ 病人具有抑郁临床表现，其中以易激怒、性兴趣减退、能力减退、睡眠障碍、兴趣丧失、绝望、生活空虚感等抑郁症状常见。临床生理指标如关节压痛数／ 指数（ Ｐ＜ ００１） 、关节肿胀数／ 指数（ Ｐ＜ ００１） 、握力（ Ｐ＝００２） 与抑郁临床表现较晨僵（ Ｐ＝ ０３２） 有更密切相关性。抑郁临床表现病人中，以高中以下文化程度者（ Ｐ＝ ００３） 、工人、农民和个体劳动者为主（ Ｐ＝ ００５） 。结论 在 Ｒ Ａ 病人中存在着严重的抑郁症状、提醒我们在今后的治疗方案选择和疗效评定上要关注病人心理和情绪。
Objective To investigate the clinical depression in patients with rheumatoid arthritis (RA) in China. Methods Ninety-five untreated patients with newly diagnosed active RA were enrolled in the self-strain depression scale (S D S). Results 53% of RA patients had clinical manifestations of depression, of which depression symptoms such as irritability, decreased sexual interest, diminished ability, sleep disturbance, loss of interest, despair and life emptiness were common. Clinical physiological indexes such as joint tenderness number / index (P <001), joint swelling index (P <001), grip strength (P = 002) and clinical manifestations of depression than morning stiffness 32) are more closely related. Among the patients with clinical manifestations of depression, those with high school education (P = 003), workers, peasants and individual laborers (P = 005). Conclusions Severe depressive symptoms are present in R A patients, reminding us that we should pay attention to the psychology and mood of patients in future treatment options and efficacy evaluation.