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采用放免法对结核性和癌性胸腔积液患者同时进行血浆和胸水内皮素（Ｅｎｄｏｔｈｅｌｉｎ，ＥＴ）含量测定。结果发现，结核性胸腔积液患者血浆ＥＴ含量明显高于正常组和癌性组（Ｐ均＜０．０１），胸水ＥＴ含量也明显高于癌性组。提示血浆和胸水ＥＴ的测定对结核性和癌性胸腔积液诊断和鉴别诊断有较高的临床价值。
The plasma and pleural effusion levels of endothelin (ET) were determined simultaneously by radioimmunoassay in patients with tuberculous and cancerous pleural effusion. The results showed that plasma ET levels in patients with tuberculous pleural effusion were significantly higher than those in normal and cancerous groups (all P <0.01), and ET contents in pleural effusion were also significantly higher than those in cancerous group. Tip plasma and pleural fluid ET determination of tuberculous and cancerous pleural effusion diagnosis and differential diagnosis of high clinical value.