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目的探讨乳腺癌前哨淋巴结状态与腋窝淋巴结状态的相关性、找出提高活检术准确性的方法。方法选取60例均为T1-2N0M0乳腺癌患者,采用美兰作为前哨淋巴结的示踪剂,注射于乳晕及肿瘤周围皮肤,5~15分钟后进行术中定位及活检术。结果全部患者均行乳腺癌改良根治术,行SLN和ALN活检,成功率96.67%(58/60),灵敏度94.44%(17/18),准确率为96.55%(56/58),假阴性率为5.56%(1/18),假阳性率5.56%(1/18)。结论前哨淋巴结活检(SLNB)能较准确的评估腋淋巴结转移,有助于保腋窝手术的开展。
Objective To explore the correlation between sentinel lymph node status and axillary lymph node status in breast cancer and find out the methods to improve the accuracy of biopsy. Methods 60 patients with T1-2N0M0 breast cancer were selected. Methylene blue was used as a tracer for sentinel lymph nodes. It was injected into the skin around the areola and the tumor. The intraoperative localization and biopsy were performed 5 to 15 minutes later. Results All patients underwent modified radical mastectomy for breast cancer. SLN and ALN biopsy were performed. The success rate was 96.67% (58/60). The sensitivity was 94.44% (17/18). The accuracy rate was 96.55% (56/58). The false negative rate was obtained. It was 5.56% (1/18) and the false positive rate was 5.56% (1/18). Conclusion Sentinel lymph node biopsy (SLNB) can accurately assess the axillary lymph node metastasis and help to maintain the operation of the fistula.