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近年来结核病死灰复燃,发病率逐年上升,已成为成人传染病中的第一杀手和最大死亡原因。我们收集了1991～1997年我科收治的结核性脑膜炎(简称结脑)30例,选择临床表现,实验室检查,治疗方案等14项参数,分析对本病预后的影响因素。 1 临床资料 30例患者经临床确诊,排除化脓性脑膜炎、病毒性脑膜炎、新隐球菌性脑膜炎。男15例,女15例,15～48岁28例,49岁以上2例。人院时病程1月以内23例,1月以上7例。全部病例均有发热、头痛。脑膜刺激征27例,意识障碍20例,颅神经损害10例(Ⅱ、Ⅲ、Ⅳ、Ⅵ、Ⅶ),椎体柬征8例,脑外结核14例(肺结核、胸腰椎结核、淋巴结结核),合并脑积水12例,抗痨前使用激素4例,不规则化疗4例,合并中晚期妊娠2例。
In recent years, the resurgence of tuberculosis, the incidence increased year by year, has become the first killer of adult infectious diseases and the largest cause of death. We collected 30 cases of tuberculous meningitis (abbreviated as tuberculous meningitis) admitted to our department from 1991 to 1997, and selected 14 parameters such as clinical manifestations, laboratory tests and treatment plans to analyze the influencing factors on the prognosis of this disease. 1 clinical data of 30 patients clinically diagnosed, excluding purulent meningitis, viral meningitis, cryptococcal meningitis. 15 males and 15 females, 15 to 48 years old in 28 cases, 49 cases over 2 cases. The course of hospitalization within January 23 cases, more than in January 7 cases. All cases have fever, headache. 27 cases of meningeal irritation, 20 cases of disturbance of consciousness, 10 cases of cranial nerve damage (Ⅱ, Ⅲ, Ⅳ, Ⅵ, Ⅶ), 8 cases of congenital heart disease, 14 cases of extracerebral tuberculosis (tuberculosis, thoracolumbar tuberculosis and lymph node tuberculosis) , 12 cases of hydrocephalus, 4 cases of hormone before anti-tuberculosis, irregular chemotherapy in 4 cases, with 2 cases of middle-late pregnancy.