甘精胰岛素联合瑞格列奈治疗疗效不佳的2型糖尿病血糖变化

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32例口服降糖药物效果不佳的2型糖尿病患者,改用联合诺和龙治疗6个月,24小时平均血糖从16.5±2.6mmol/L降至7.9±2.3mmol/L,空腹血糖(FPG)从11.2±3.6mmol/L降至5.9±1.6mmol/L,餐后2小时血糖(PPG)从18.1±4.9mmol/L降至10±2.8mmol/L,血糖>10mmol/L时间百分比从62.5±16.6%降至22.3±11.3%,HbA1C从11.8±1.6%降至6.8±1.3%,低血糖从0增加至5次,来得时平均剂量28.1±4.9U/d,诺和龙平均剂量206.64±35.8mg/餐,患者体重指数无明显变化.
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