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本文作者认为,营养素缺乏存在两种类型。Ⅰ型营养素缺乏的特点是,组织中营养素含量的减少伴有一个或多个特殊代谢途径的缺陷。Ⅱ型营养素缺乏的特点是,原发性因素导致生长迟缓或停止,但不伴有组织中该营养素含量的降低,也不伴有可供诊断的临床特异症状和体征。锌的缺乏属于后者。作者认为,红细胞金属硫蛋白-I是诊断人体锌缺乏的敏感指标,它与血浆锌结合可用于诊断锌缺乏。
The authors believe there are two types of nutrient deficiency. The lack of type I nutrients is characterized by a reduction of nutrients in the tissue with the attendant deficiencies of one or more specific metabolic pathways. A deficiency of type II is characterized by a delay or slowing of growth due to a primary factor but not associated with a decrease of the nutrient in the tissue nor with the clinically specific symptoms and signs that are available for diagnosis. The lack of zinc belongs to the latter. The author believes that erythrocyte metallothionein-I is a sensitive indicator of the diagnosis of zinc deficiency in the body, which in combination with plasma zinc can be used to diagnose zinc deficiency.