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氯氮平自临床应用不久(1975年)因出现粒细胞缺乏症(简称粒缺)使其推广严格受限。其后的临床试验表明氯氮平对传统的
Clozapine shortly since its clinical application (1975) due to the emergence of agranulocytosis (referred to as the lack of grain) to promote its strictly limited. Subsequent clinical trials showed that clozapine was traditional