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人乳头状瘤病毒 ( HPV)结构蛋白 L 1 (主要 )和 L2 (次要 )具有中和表位 ,抗 L1抗体为型特异性 ,抗 L 2抗体则有交叉中和作用 ,可识别推定的共同中和表位。已知 1 6型 HPV次要核壳蛋白 L2的 1 0 8～ 1 2 0位氨基酸 ( aa)区存在着 6和 1 6型 HPV的共同交叉中和表位 ,提示含该表
The human papilloma virus (HPV) structural proteins L 1 (major) and L2 (minor) have a neutralizing epitope, the anti-L1 antibody is type-specific and the anti-L 2 antibody has a cross-neutralizing effect recognizing putative Common neutralizing the epitope. It is known that a region of amino acids (aa) 108 to 120 of HPV 16 nucleocapsid protein is known to have common cross-neutralizing epitopes of HPV types 6 and 16, suggesting that this table