乳腺癌是女性常见的恶性肿瘤 ,近年来国内乳腺癌发病有上升趋势。乳腺癌肿瘤标志物在乳腺癌的早期诊断、治疗选择、治疗监测、复发和转移监测、疗效评价和预后估价以及群体随访观察和普查等方面有重要意义。近年来免疫学、生物化学、分子生物学、细胞工程学和遗传工程学及其相 Breast cancer is a common malignant tumor in women. In recent years, the incidence of breast cancer in the country has risen. Breast cancer tumor markers are of great significance in the early diagnosis of breast cancer, treatment options, treatment monitoring, recurrence and metastasis monitoring, therapeutic evaluation and prognostic evaluation, as well as group follow-up observation and screening. In recent years, immunology, biochemistry, molecular biology, cell engineering and genetic engineering and their relatives