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患者女,30岁,因盆腔炎口服泰利必妥100mg,约半小时突感全身发痒、起疹,继而头晕、胸闷、气短、心慌、呕吐,立刻来院急诊。既往体健,否认药物过敏史。体查:体温36.6℃,呼吸33次/分,血压6.65/4.26kpa,患者高度烦燥,周身皮肤潮红,遍体云片状丘疹,眼睑及面部浮肿,双结合膜充血,口唇发绀,双肺呼吸变粗,心率48次/分,心音低沉,可闻期前收缩5—8次/分,四肢冷。当即停服该药,按过敏性克予以积极论:①吸氧;1:1000肾上腺素0.5mg肌注;10％葡萄糖酸钙20ml静脉推注;氢化考的松100mg、维生素C1g、10％氯化钾10ml加入10％葡萄糖液500ml静滴,20分钟后四肢转暖,心率恢复至78次/分,血压17.29/10.64
Female, 30 years old, due to pelvic inflammatory disease oral telbital 100mg, about half an hour suddenly felt the whole body itchy, rash, and then dizziness, chest tightness, shortness of breath, palpitation, vomiting, and immediately hospital emergency. Past physical health, denied the history of drug allergies. Physical examination: body temperature 36.6 ℃, breathing 33 beats / min, blood pressure 6.65 / 4.26kpa, the patient was extremely irritable, whole body skin flushing, all over the clouds papular eyelid and facial edema, double conjunctival hyperemia, lips cyanosis, lungs Breathing thick, heart rate 48 beats / min, low heart sounds, can be heard before the contraction of 5-8 beats / min, cold limbs. Immediately stop taking the drug, according to allergic grams to be positive: ① oxygen; 1: 1000 epinephrine 0.5mg intramuscular injection; 10% calcium gluconate 20ml intravenous bolus; hydrocortisone 100mg, vitamin C1g, 10% chlorine Potassium 10ml 10% glucose solution 500ml intravenous infusion, limbs warm after 20 minutes, heart rate returned to 78 beats / min, blood pressure 17.29 / 10.64