近年来研究发现调节性T细胞(Treg)在妊娠维持中诱导母胎免疫耐受方面起着极其重要的作用,其平衡失调将可能影响妊娠结局〔1〕。Th17细胞和Treg细胞是CD4+T细胞的两个不同亚型,二者在分化过程中具有相关性,然而在功能上互相拮抗〔2〕。随着免疫学研究的进展,人们逐步认识到正常妊娠是一个 In recent years, studies have found that regulatory T cells (Tregs) play an important role in the induction of maternal immunocompromise during pregnancy maintenance, and their imbalance may affect pregnancy outcome [1]. Th17 cells and Treg cells are two different subtypes of CD4 + T cells, both of which are involved in the process of differentiation but are functionally antagonistic to each other (2). With the progress of immunological research, people gradually realize that normal pregnancy is one