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目的:探索宫颈癌放疗中癌细胞凋亡的细胞学形态变化以及凋亡指数与预后关系;方法:检测30例有复查资料的宫颈癌放疗1周(10GY)时阴道涂片做凋亡癌细胞计数及预后对照;结果:复发组凋亡细胞指数<5者占66.7%,>10者占11.1%。未复发组<5者占9.5%,>10者占61.9%;结论:宫颈癌放疗早期(10G6)时阴道细胞学提示,凋亡癌细胞高指数者(>10)放疗预后好,而低指放数者(<5)者放疗后易在短期内复发。阴道细胞学检测癌细胞凋亡指数可做为判断预后的一项指标
Objective: To explore the cytological changes of apoptosis of cancer cells during cervical cancer radiotherapy and the relationship between apoptosis index and prognosis.Methods: 30 cases of recurrent cervical cancer were treated with vaginal smears for 10 days Count and prognosis control; Results: Apoptotic cell index of recurrence group <5 accounted for 66.7%,> 10 accounted for 11.1%. No recurrence group accounted for 9.5%, <10 accounted for 61.9%; Conclusion: cervical cancer early radiotherapy (10G6) vaginal cytology prompted a high index of apoptotic cancer cells (> 10) good prognosis of radiotherapy , While those with low indications (<5) were likely to relapse within a short period of time after radiotherapy. Vaginal cytology detection of cancer cell apoptosis index can be used as an indicator of prognosis