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本文对21例百岁老人(100～106岁)和21例老年人(65～78岁)进行了血浆游离氨基酸浓度、淋巴细胞转化率及有关细胞遗传学等方面的比较研究。结果显示:百岁老人组除瓜氨酸和胱氨酸较高(P<0.05)外,另22种氨基酸、苯丙/酪氨酸克分子比、必需氨基酸总和(不含色氨酸)、24种游离氨基酸总和、淋巴细胞转化率及其分裂指数、染色体自发畸变率和姊妹染色单体交换率与老年对照组比较,均无统计学差异。并根据观察结果,对百岁老人的长寿因素进行了讨论。
In this paper, 21 cases of centenarians (100 ~ 106 years old) and 21 elderly (65 ~ 78 years old) were compared in plasma free amino acid concentration, lymphocyte transformation rate and related cytogenetics. The results showed that in addition to citrulline and cystine (P <0.05), the ratio of the other 22 amino acids, the molar ratio of phenylpropylamine / tyrosine, the sum of essential amino acids (excluding tryptophan) 24 kinds of free amino acids, lymphocyte transformation rate and its division index, spontaneous chromosome aberration rate and sister chromatid exchange rate compared with the elderly control group, no significant difference. Based on the observation, the longevity factors of centenarians were discussed.