论文部分内容阅读
以血吸虫病流行地区和非流行地区常住居民1175人为对象,用ELISA法检测HBV、HCV血清学标志,用快速双抗体夹心ELISA检测抗体判断血吸虫感染。结果,流行地区感染率分别为:HBV(63.8%)、抗-HCV(2.2%),血吸虫(70.2%);非流行地区感染率分别为HBV(49.7%),抗-HCV(0.9%),血吸虫(5.2%)。共检测490人血吸虫抗体,阳性176人(35.9%),阳性者HBV、HCV、肝硬变率显著高于阴性者。HBV、HCV,血吸中两种以上合并感染,均较单独感染对肝功能及肝硬变影响大,合并感染比上述感染阴性者的肝硬变患病率增长3.7-7.1倍,并发现HBV与血吸虫感染有相加致癌作用。
The target population was 1,175 permanent residents in epidemic areas and non-endemic areas of schistosomiasis. HBV and HCV serological markers were detected by ELISA and antibodies against schistosomiasis were detected by rapid double antibody sandwich ELISA. As a result, the prevalence rates in the prevalent areas were: HBV (63.8%), anti-HCV (2.2%), and schistosomiasis (70.2%); the prevalence in non-endemic areas was HBV (49.7%). Anti-HCV (0.9%), Schistosoma (5.2%). A total of 490 schistosomiasis antibodies were detected, 176 (35.9%) were positive, and the HBV, HCV, and cirrhosis rates were significantly higher in the positive than in the negative. Two or more co-infections of HBV, HCV, and blood-sucking had a greater impact on liver function and cirrhosis than single infections. The prevalence of liver cirrhosis was 3.7-7.1 times higher in patients with co-infection than in those with negative infections. , And found that HBV and schistosome infection have additive carcinogenic effect.