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选择我院2012年3月~2014年5月收治的86例难治性癫痫患者为研究对象,随机分为对照组43例,观察组43例,对照组行卡马西平与托吡酯治疗,观察组在对照组治疗基础上联合左乙拉西坦治疗,对两组患者的临床疗效进行分析。结果治疗前,两组患者的癫痫发作次数无明显差异,经治疗后,两组患者均有改善,但是观察组明显优于对照组,差异有统计学意义(P<0.05);观察组治疗有效率93.02%,对照组为72.09%,差异有统计学意义(P<0.05)。采取左乙拉西坦联合托吡酯、卡马西平治疗难治性癫痫疗效显著,安全性高,可减少癫痫发作次数,值得临床进一步推广使用。
A total of 86 patients with refractory epilepsy who were treated in our hospital from March 2012 to May 2014 were selected and randomly divided into control group (43 cases) and observation group (43 cases). The control group was treated with carbamazepine and topiramate, and the observation group In the control group based on the combination of levetiracetam treatment, the clinical efficacy of the two groups were analyzed. Results Before treatment, there was no significant difference in the number of epileptic seizures between the two groups. After treatment, both groups improved, but the observation group was significantly better than the control group (P <0.05) Efficiency 93.02%, control group was 72.09%, the difference was statistically significant (P <0.05). To take levetiracetam combined with topiramate, carbamazepine refractory epilepsy treatment of significant effect, high safety, can reduce the number of seizures, it is worth further clinical use.