在天然产物合成和结构的研究中,常常会涉及分子的立体构型问题,目前虽能用核磁共振谱及X衍射法等物理方法进行测定,然而用化学方法测定构型则不需特殊的仪器,且方法又简便,所以仍有一定的应用性。为此,Kagan撰写了这一论题的专著进行 In the study of the synthesis and structure of natural products, the problem of the stereoconfiguration of the molecule is often involved. Although it can be determined by physical methods such as nuclear magnetic resonance and X-ray diffraction, it is not necessary to use special instruments to determine the configuration by chemical methods , And the method is simple, so there is still some applicability. To this end, Kagan wrote a monograph on this topic