我们用中药降脂软化汤治疗冠心病心绞痛,脑动脉硬化均取得了较为满意的效果。为了探讨降脂软化汤对动脉粥样硬化作用机理,我们进行了动物实验,现将实验所得结果报告如下。材料和方法新西兰大耳白家兔45只,体重2.5kg左右,雌雄兼有。用本实验室基础饲料稳定30天后,采用传统的胆固醇喂饲法造模型。实验开始前普测血脂值,40只动物给化学纯胆固醇0.5g/只/日。均在清晨进食前与少量基础饲料搅拌空腹喂饲。5只作为正常对照组只给基础饲料。每月分别测血脂、体重一次。41天、60天和75天用气体栓塞分别处死雌雄各1只动物,可见主动脉、主动脉瓣环、肺动脉 We used traditional Chinese medicine lipid-lowering softening soup to treat coronary heart disease angina, cerebral arteriosclerosis have achieved satisfactory results. In order to investigate the mechanism of the effect of Jiangzhi Softening Decoction on atherosclerosis, we conducted an animal experiment. The results of the experiment are reported below. Materials and Methods 45 New Zealand big-eared white rabbits weighing about 2.5 kg, both male and female. After stable for 30 days with the basic feed of this laboratory, the model was made using the traditional cholesterol feeding method. The blood lipid values ​​were measured before the start of the experiment, and 40 animals gave chemical pure cholesterol 0.5 g/only/day. Both fasted with a small amount of basal feed before fasting in the morning for fasting. 5 only served as basal diet as normal control group. The blood lipids and body weight were measured once a month. Males and females were sacrificed by gas embolism at 41 days, 60 days and 75 days respectively. The aorta, aortic annulus, and pulmonary artery were visualized.