目的：慢性肾衰常伴有严重的细胞免疫功能缺陷，笔者试图用绞股蓝改善慢性肾衰维持血透患者细胞免疫功能缺陷。方法：３９例患者随机分为两组，治疗组服用绞股蓝６０ｍｇ，每日三次。对照组常规治疗。分别于６周前后抽外周血测Ｔ淋巴细胞亚群。结果：治疗组用药前ＣＤ３、ＣＤ４、ＣＤ８分别为：５２．２８±４．６２、２９．２６±３．３８、２４．２３±３．５３，治疗后分别为：５６．８２±５．４、３１．０４±３．９２、２５．６２±３．４７，其中ＣＤ３升高有非常显著差异（Ｐ＜０．０１），ＣＤ４升高有显著差异（０．０１＜Ｐ＜０．０５）。对照组疗程前ＣＤ３、ＣＤ４、ＣＤ８分别为：５５．４４±５．０６、３０±３．５４、２４．８１±３．２３，疗程后分别为：５２．３１±５．１６、２９．６９±３．８８、２５．０６±２．７７。结论：绞股蓝可升高慢性肾衰维持血透患者ＣＤ３、ＣＤ４，并使患者精力体力得到改善 OBJECTIVE: Chronic renal failure is often accompanied by severe defects in cellular immune function. The authors attempted to use gynostemma pentaphyllum to improve the maintenance of chronic renal failure and maintain the defects of cellular immune function in hemodialysis patients. Methods: Thirty-nine patients were randomly divided into two groups. The treatment group took Gynostemma 60 mg three times daily. The control group was treated routinely. Peripheral blood T-lymphocyte subsets were collected before and after 6 weeks. Results: Before treatment, CD3, CD4, and CD8 were 52.28±4.62, 29.26±3.38, and 24.23±3.53, respectively, and they were: 56.82±5.4 after treatment. 31.04±3.92, 25.62±3.47, among which there was a significant difference in the elevation of CD3 (P<0.01), and there was a significant difference in the elevation of CD4 (0.01