HBsAg持续阳性者的传染性问题,新生儿的母子间垂直感染受到重视,虽有父子间感染的报告,但也多为新生儿和乳儿。HBsAg持续阳性者的配偶抗-HBs检出率颇高,作者的观察为60%,比对照组的20～30%为高,因而提示配偶间水平感染的存在。但配偶间感染发病的则罕见,本文报告1例婚 The infection of persistent HBsAg positive people, the newborn’s vertical infection between mother and child attention, although there are reports of infection between father and son, but also mostly newborn and baby. The spouse with HBsAg persistent positive spouse anti-HBs detection rate is high, the author’s observation was 60%, 20-30% higher than the control group, thus suggesting the existence of horizontal infection between spouses. However, the incidence of spousal infection is rare, this article reports 1 case of marriage