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本文取自250例慢迁肝的肝穿刺组织,结合临床及免疫学检查,按组织学改变可明确诊断慢性小叶性肝炎(CLH)者40例,占慢迁肝的16.0%。CLH的主要组织学表现为肝细胞疏松、肝板排列拥挤和肝窦狭窄,呈铺路石状。嗜酸性小体检出率为60.0%及小叶内有不同程度的炎细胞浸润。半数以上的病例可见散在或灶性均匀体状肝细胞,此乃慢性HBsAg携带状态的有力佐证。CLH是慢迁肝的一种表现形式,它与急性小叶性肝炎虽有类似之处,但可以鉴别。
In this paper, 250 cases of liver metastasis from slow liver transplantation, combined with clinical and immunological examination, histological changes can be clearly diagnosed in 40 cases of chronic lobular hepatitis (CLH), accounting for 16.0% of slow-moving liver. The main histological manifestations of CLH were hepatocellular loosening, hepatic plate crowding and sinusoidal stenosis in the shape of paving stones. The detection rate of eosinophils was 60.0% and there were different degree of infiltration of inflammatory cells in the lobules. More than half of the cases can be seen in scattered or focal homogeneous somatic liver cells, which is a powerful evidence of chronic HBsAg carrier status. CLH is a manifestation of slow migration of the liver, although it is similar to acute lobular hepatitis, but it can be identified.