IgE参与速发型变态反应的作用已是无疑的事实,它是通过抗体的Fc部份结合到具有高度特异的肥大细胞和嗜碱细胞的Fc受体上,当它和多价抗原或抗IgE抗体交联时,即激发过敏介质的释放,出现一系列过敏症状。作者使用大鼠IgE免疫BABB/c小鼠,取免疫小鼠的脾细胞和非分泌型的浆细胞瘤P3X63Ag8.653细胞,在PEG作用下融 The role of IgE in the immediate onset of allergic reactions has been undoubtedly evidenced by its binding to the Fc receptor with highly specific mast cells and basophils by the Fc portion of the antibody when it binds to multivalent antigens or anti-IgE antibodies Cross-linked, that is, stimulate the release of allergic media, a series of allergic symptoms. The authors used rat IgE immunization of BABB / c mice, immunized mice spleen cells and non-secreting plasma cell tumor P3X63Ag8.653 cells, under the action of PEG melt