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我们于1979~1982年间,在蚌埠地区对222例糖尿病患者的家谱作了研究.本组糖尿病阳性家族史的发生率为10.8%.糖尿病的遗传方式为多基因遗传,除2个连续世代(遗传)符合于常染色体显性遗传的理论(假设).糖尿病的遗传度为50.94%,这似可提示在糖尿病的发病上有遗传和环境因素的相关作用.
We studied the pedigree of 222 diabetic patients in Bengbu from 1979 to 1982. The prevalence of diabetes-positive family history in this group was 10.8% .The genetic pattern of diabetes was polygenic, with the exception of 2 consecutive generations ) Conformed to the theory of autosomal dominant inheritance (hypothesis). The heritability of diabetes was 50.94%, suggesting that genetic and environmental factors may play a role in the pathogenesis of diabetes.