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通过追访调查1949～1976年有地址可查的213例门诊银屑病患者的病程,除发现本病的一般特点外,经统计分析发现病情轻重与性别、发病年龄、发病形式、就诊早晚、有无家族史及是否嗜酒均无关,而与病程长短及是否应用抗癌药有明显关系。使用抗癌药虽对本病暂时有效,但最终可能使其病情显著加重。故应慎用或不用。此外,在213例患者中有7例患了恶性肿瘤,比当地同年龄正常人群发病率高8.4倍,经统计学处理有非常显著差异。11例死亡病例中有5例死于恶性肿瘤。这可能是银屑病患者有好发恶性肿瘤的倾向,今后应进一步重视银屑病与恶性肿瘤的关系。
Through the follow-up survey from 1949 to 1976, the address of 213 cases of outpatient psoriasis course of the disease, in addition to the general characteristics of the disease, the statistical analysis found that the severity and gender, age of onset, the incidence of form, treatment sooner or later, Whether the family history and whether alcohol has nothing to do with the duration and application of anticancer drugs have a clear relationship. Although the use of anticancer drugs temporary effect of the disease, but in the end may make its condition significantly worse. It should be used with caution or not. In addition, 7 out of 213 patients developed malignancy, a 8.4-fold higher incidence than the local normal population at the same age, with significant differences statistically observed. Five of the 11 fatalities died of malignancy. This may be psoriasis patients have a tendency to malignant tumors, the future should pay more attention to the relationship between psoriasis and malignant tumors.