奎宁常用于治疗重症恶性疟患者,通常的治疗方法是先用静脉滴注,此法需几小时后血内才达到治疗浓度。在缅甸当缺少滴注瓶时,用静脉注射奎宁抢救了许多患者。但有些学者认为,静脉注射方法可能导致血浆内奎宁达到中毒水平,或血液中奎宁刺激郎格罕氏岛使产生更多胰岛素而引起低血糖。据White等最初报道用大剂量奎宁患者耐 Quinine is commonly used in patients with severe falciparum malaria, the usual treatment is to use intravenous drip, this method takes a few hours to reach the therapeutic concentration within the blood. In Myanmar, quinine was administered intravenously to rescue many patients when lack of drip bottles. However, some scholars believe that intravenous injection may lead to poisoning levels of quinine in plasma, or that quinine in the blood stimulates Langerhan Island to produce more insulin and cause hypoglycemia. According to White et al., It was originally reported to be resistant to high-dose quinine