端粒酶在 85 %以上的各类恶性肿瘤中激活并维持细胞的无限增殖能力 ,是目前发现的恶性肿瘤细胞区别于正常细胞最广谱的分子标记 ,具备了作为肿瘤靶向基因治疗的物质基础。因此 ,端粒酶已成为肿瘤基因治疗的理想靶点 ,有望为肿瘤基因治疗提供一种全新的途径 Telomerase activity in more than 85% of all types of malignant tumors to activate and maintain the cell’s ability to proliferate is the most widely observed molecular marker of malignant cells differentiated from normal cells and possesses the potential as a tumor-targeted gene therapy basis. Therefore, telomerase has become an ideal target for gene therapy of cancer and is expected to provide a completely new approach to tumor gene therapy